What we do
What is FerroTrace?
FerroTrace is a new super-paramagnetic iron-oxide nanoparticle (SPION) tracer designed to enable the surgeon to accurately map the lymphatic system with a laparoscopic or robotic camera. Used in combination with Indocyanine Green Dye (ICG), FerroTrace assists in the identification of sentinel lymph nodes for precisely targeted surgical excision.
FerroTrace takes the same path through the lymphatic system as metastasising cancer cells and is designed to be retained in the first draining lymph nodes − the sentinel lymph nodes. Designed to enable highly accurate detection of affected lymph nodes:
- Before surgery – using MRI
- During/after surgery – using the FerroMag magnetometer
How it works
Our unique patented technology is a new-generation, polymer-coated magnetic nanoparticle.
This nanoparticle drives a magnetically guided imaging system designed to precisely identify sentinel lymph nodes, to assist surgeons and pathologists to more accurately stage solid tumours and locate and address micro-metastases that may otherwise go undetected.
Dr Naruhiko Ikoma
Assistant Professor, Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX
Current gastric cancer treatment lacks an effective strategy to tailor surgical and pathological assessment.
FerroTrace has tremendous potential to establish such a strategy, through novel techniques of sentinel lymph node biopsy.
What are the benefits
of using FerroTrace?
Compared with currently available tracers, FerroTrace is designed to be:
Designed to be used with a near infrared (NIR) surgical camera and magnetometer after a single injection; and to be detected by MRI
No radiation exposure to the patient or staff
Easy To Use
No half-life, eliminates time-sensitive logistical issues seen with radioisotope tracers
Designed for rapid uptake in lymph nodes. Visible in minutes with long term retention over weeks
Designed to be used with existing surgical laparoscopic and robotic NIR cameras to identify potential sentinel nodes during surgery
Dr Giri Krishnan
Otolaryngology, Head and Neck Surgery Registrar
Ferrotrace nanoparticles have been fine-tuned with respect to size, shape and chemical composition to navigate the complex lymphatic pathways in the head and neck and are designed to leverage the benefits of improved spatial resolution of MRI.